As a multidisciplinary professional he has to deal with a series of tasks that are not only limited to drug dosage but also include the administration of clinical pharmacy resources and interaction with doctors nurses and patients. In addition to precision performing these tasks requires multiple knowledge medical/scientific administrative pharmacological among others. However the overload of tasks and fatigue can lead the clinical professional to error with drug interactions being one of the most feared. Studies reveal that 15% of elderly patients suffer some harm due to drug interactions and 70% of ICU patients have significant interactions within 24 hours of admission.
The occurrence may not only increase the average length of stay from 8 to 20 days but also cost health institutions around R$10000 per adverse outcome resulting from the interaction. In this article you will learn about drug interactions for example tips to prevent this clinical event from occurring and learn about a resource that can help improve clinical pharmaceutical [Se connecter pour voir le lien] practices. What is drug interaction? Elderly woman taking various medicines Image iStock. A drug interaction is characterized as a clinically relevant change in the absorption action or elimination of drugs that can occur when another substance pure or compound is administered to the patient. This event can occur between drugs or between a drug and some food. With this interaction drugs can either lose their effectiveness or have their effects potentiated.
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In addition there is a risk of generating the dreaded adverse effects including bleeding convulsions loss of efficacy drowsiness toxicity among other symptoms depending on the chemical combination. Example of drug interaction Patient admitted to the ICU and undergoing drug treatment Image Canva. A 60-year-old patient comes to the emergency department with fever cough and dyspnea. An X-ray examination showed pulmonary alveolar infiltrate and the medical team diagnosed him with community-acquired pneumonia. As the patient has not needed antibiotics for at least three months he has no risk factors for resistant Streptococcus pneumoniae and does not meet the criteria of CURB-65 (a mortality prediction scale). Thus Clarithromycin 500 mg is prescribed to be taken orally twice a day for 7 days.